Determination of nanoscale AIE and unique combination of FRET effect solubilisation position

One surfactant as of today the most widely solubilizers, are widely used for environmental remediation, decontamination cleaning, crude oil, catalysis, analysis and detection, drug delivery and emulsion polymerization art. Substance which is solubilized in the surfactant micelles in a position to achieve the above solubilizing various solubilizing critical applications. At present, mainly based on the establishment – determined relationship \”polar probe signal micellar environment polar region\” solubilized micellar solubilization substances in position. Due to the uncertainty of the response performance difference probe and polar microenvironment polarity micelles, the measurement result of the method would appear contradictory. Meanwhile, similar polarity probes, methods for the determination difficult to compare their solubilization fine position. To solve this measurement problem, Beijing University of Chemical Technology, Professor Lu Chao research team combined with aggregation induced emission (AIE) and fluorescence resonance energy transfer (FRET), designed the which does not involve a probe pole the new high-precision measurement and micellar microenvironment method . Related outcomes to \”Measurement of Solubilization Location in the Micelles Using Anchored Aggregation-Induced Emission Donors\” in the title, published in \” Angew. Chem. Int. Ed. \” on (Angew. Chem. Int. Ed. 2020, https://doi.org/10.1002/anie.202005085).

In nuclear AIE micelle structure

The first group of four light emitting AIE styrene (TPE) covalently modified to cationic surfactant eicosyl triethylammonium bromide (C10TEAB) a trailing end, Synthesis surfactant TPE-C10TEAB. Transmission electron microscopy, dynamic light scattering results and theoretical calculations show that, TPE-C10TEAB capable of forming a diameter of about 5 nm spherical micelle in water, TPE luminophore is anchored in the center of the micelle (FIG. 1). AIE与FRET的巧妙结合实现增溶位置的纳米级测定

using the FRET measurement distance formula solubilizing position

Unlike aggregate fluorescence quenching (ACQ) luminophores, TPE core of micelles polyRally increasing fluorescence quantum yield, fluorescence emitted intense blue. With efficient light emission state of aggregation TPE as FRET donor, as material solubilized FRET acceptor, it can be accurately calculated by known FRET donor FRET distance formula – nanoscale distance receptors, thus in the nanoscale measured solubilized material solubilizing position (FIG. 2). Even solubilized material of a similar nature, can also be fine in comparison to its position solubilizing micelles. The entire assay probe without interference polar microenvironment and micelles. Further, by comparing the solubilized material and solubilization properties known location, location solubilized solubilized within the micelles substance depends on its size; the micelle surface located larger size solubilized substances which increase solution depends on the position of its hydrophobicity. AIE与FRET的巧妙结合实现增溶位置的纳米级测定

polychromatic white light emission solutions and gels

the FRET behavior solubilized by regulating substances, can easily build a multicolor light emission and pure white solution. Agarose gel micellar nanoparticles causes rapid fixation, the emission characteristics can be maintained in solution form micelles prepared and pure white light emitting polychromatic gel (FIG. 3).

AIE与FRET的巧妙结合实现增溶位置的纳米级测定
FIG. 3. (a) a multicolor light emission solutions and gels, (b) white light-emitting solutions and gels, (c) a white light emission was CIE coordinates, (d) a white light emitting CIE gels coordinates

in summary, based on \”solubilized matter – solubilization position – micellar microenvironment\” establishment of the relationship, not only help better understand the nature of the substance to be solubilized solubilization relationship between the position, provide strong theoretical guidance for solubilizing applications; also provides a new direction for further development of simple and efficient design and potential applications of micellar solubilizers. This article is the first author School of Chemistry Professor Jiang Fu Wei tube , second author is a graduate YANG Ting-ting (Instructor tube WeiJiang is Associate Professor), corresponding author is a professor at Lu Chao [ 123], Beijing University of Chemical Technology as the only complete units. This work was funded by Fundamental Research and the National Natural Science Foundation of Central Universities.

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