Summary of project is Di Yuanshi team, South China: Based on the macromolecular bricks method of self-assembling molecules music

华南理工程正迪院士团队综述:基于分子乐高积木方法的大分子自组装 In recent years, self-assembled macromolecules made rapid development, and is widely used in drug, nanolithography, catalysis, molecular electronic devices, sensors and the like. As we all know, the material properties and functions not only related to the chemical composition of the material, but also the internal structure of different scales are closely related. Small differences in chemical structure may cause great differences on the assembly structure and function. In recent years, with the \”click\” the development of the reaction, having a specific shape and force to be accurately synthesized macromolecules. These macromolecules having a specific shape interaction exhibit diverse behaviors novel assembly, the assembled structure and functions. Recently, Professor South China Institute for Advanced Soft Matter Science and Technology ZD Cheng Task Force and Professor Huang Mingjun research group [123 ], polymer science journals top Summary Progress in polymer Science table issued entitled \” the role of architectural engineering in macromolecular self-assemblies via non-covalent interactions: review article a molecular LEGO approach \”a. The paper and comprehensive summary of the assembly behavior of polymer macromolecules, dendrimers, giant molecules, colloids, and the like from the viewpoint of the DNA and protein engineering system configuration, emphasis focused on the self-assembled macromolecules cycle and quasi-periodic structure . South China University of Technology is the first article units, Dr. Suze Bin as the first author , co-corresponding author Professor Stephen ZD Cheng and Professor Huang Mingjun for the article. In this article, the authors propose a new concept: a simple building blocks (building blocks) can be assembled into primitives macromolecules (macromolecular motifs) having a complex structure and interaction of these molecules primitives by non-covalent force further assemble into ordered structures . This process LegoBuilding blocks of stitching there are many similarities, also known as Lego methods. The overall shape of the article to which the building blocks are divided into five categories, namely, polymer coils, dendrimers, rod-like molecules, discotic molecule and a polyhedron (Table 1). It may be five basic building blocks of the same category or across a combination of compositions, can be obtained a total of 15 combinations (FIG. 1), a polymer of two or more coils can be constructed, for example, a block copolymer; high polyhedral Nanomolecular giant molecules coils may be constructed of a surfactant; and a polymer of the discotic liquid crystalline polymer coils can be constructed; dendrimer molecule may be configured with polyhedrons nano dendritic giant molecule; discotic molecules may be formed with nano polyhedral shape giant amphiphilic body; nanomolecule more polyhedron may be formed like a giant polyhedron. The article describes in detail the fifteen primitives macromolecular assembly behavior, with particular emphasis on structural and related functional description of assembly.

华南理工程正迪院士团队综述:基于分子乐高积木方法的大分子自组装 FIG. 1, constructed based polymer coils, dendron, polyhedral molecules, rod-like molecules, discotic modules 15 can be constructed of macromolecular primitives. This macromolecular group 15 elements listed in the middle of the corresponding arrow or double arrow.
华南理工程正迪院士团队综述:基于分子乐高积木方法的大分子自组装 Table 1 classification, five common building blocks
Since Staudinger put forward the hypothesis of macromolecules, polymer science has been developed and prosperous especially linear polymer to change our lives with all aspects. Macromolecules having a specific shape and interaction force to further expand the diversity of the structure and function of the macromolecular material. At the end of the article, the author constructs macromolecules based on Lego law put forward several challenges and prospects. We should first module further expand the toolbox configuration, e.g. cage-like organic molecules, metal – organic composite cage, accurate inorganic clusters, metallic nanoparticles, etc., and the further development of biological macromolecules such as DNA, proteins and the like in the method used. Second, compared to many sophisticated structures that exist in nature, man-made design of macromolecular self-assembly is still in the initial stage, complete control of multi-level complex of two-dimensional self-assembled, three-dimensional structure remains a challenge. Finally, since the relationship between performance macromolecular structure assembled with a particular biological, mechanical, electrical, magnetic, and other aspects not fully understood. Faced with these challenges, multidisciplinary cooperation frontier indispensableLess, including but not limited to theoretical and experimental physics, computer simulations, advanced and accurate to the chemical synthesis of chemical and biological characterization methods. There is no doubt that such macromolecules having a specific shape and the force will be a class of widely applicable, even in new materials with novel properties. Article link: https: //www.sciencedirect.com/science/article/pii/S007967002030023X

相关新闻