Wireless charging electrochemiluminescence hydrogel – new source remote activation light-sensitive protein

I believe we will not be unfamiliar to charge wireless phones, this new charging way so that we get rid of the shackles of the charging cable, simply attach the phone to the charging base can be achieved for charging mobile phones, the principle here is that we used known electromagnetic induction, which has a large penetration depth characteristics. Recently, Institute of Chemistry Lvfeng Ting et al The wireless charging system prepared using ECL electromagnetic induction successful remote activation light-sensitive protein , with than those with traditional methods of near-infrared light to activate a greater depth penetration, light field of genetics promising tool. In a polyacrylamide hydrogel baseload classical luminol electrochemiluminescence member , the wireless charging may produce a unique persistent emission, the emission spectrum of luminol 390-540 nm, excitation photosensitive satisfied conditions of ChR2 protein. They constructed successfully transfected cells sensitive protein ChR2 confocal image display successfully transfected cells expressing ChR2-MoRED protein, ChR2 physiological experiments demonstrate results of the electrical holding properties sensitive to light. Is activated luminol chemiluminescence, of the extracellular calcium ions flow passage ChR2, may be intracellular calcium indicator Fluo-8 detected. After screening conditions set by the wireless charging transmitter 6V DC voltage supply means, the receiving apparatus can be stabilized output voltage of 5 V in the case of of 1.6 cm, and realize the remote-control light-sensitive protein .

FIG Immunofluorescence a confocal image; FIG b is electrophysiological experiments.
The wireless charging device to stimulate and activate the hydrogel ECL emission light sensitive ChR2 channel

We believe that this wireless remote activation charging method of light-sensitive protein the new strategy will bring to light the field of genetics, it is expected to overcome the lack of near-infrared light penetration depth limitations. Meanwhile, the wireless charging device also applicable to other areas that require an internal light source, such as in deep tissue irritation photosensitive reactive oxygen molecules. Original link: https: //pubs.acs.org/doi/pdf/10.1021/acsami.0c07476